Potentiation of Low-Dose Doxorubicin Cytotoxicity by Affecting P-Glycoprotein through Caryophyllane Sesquiterpenes in HepG2 Cells: An In Vitro and In Silico Study

Doxorubicin represents a valuable choice for different cancers, although the severe side effects occurring at the high effective dose limits its clinical use. In the present study, potential strategies to potentiate low-dose doxorubicin efficacy, including a metronomic schedule, characterized by a s...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Di Sotto, Antonella, Irannejad, Hamid, Eufemi, Margherita, Mancinelli, Romina, Abete, Lorena, Mammola, Caterina Loredana, Altieri, Fabio, Mazzanti, Gabriela, Di Giacomo, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014471/
https://ncbi.nlm.nih.gov/pubmed/31963614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020633
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