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Molecular and Regulatory Mechanisms of Desensitization and Resensitization of GABA(A) Receptors with a Special Reference to Propofol/Barbiturate

It is known that desensitization of GABA(A) receptor (GABA(A)R)-mediated currents is paradoxically correlated with the slowdown of their deactivation, i.e., resensitization. It has been shown that an upregulation of calcineurin enhances the desensitization of GABA(A)R-mediated currents but paradoxic...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kang, Youngnam, Saito, Mitsuru, Toyoda, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014398/
https://ncbi.nlm.nih.gov/pubmed/31952324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020563
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