SV40 Transfected Human Anterior Cruciate Ligament Derived Ligamentocytes—Suitable as a Human in Vitro Model for Ligament Reconstruction?

Cultured human primary cells have a limited lifespan undergoing dedifferentiation or senescence. Anterior cruciate ligaments (ACL) are hypocellular but tissue engineering (TE) requires high cell numbers. Simian virus (SV) 40 tumor (T) antigen expression could extend the lifespan of cells. This study...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Schulze-Tanzil, Gundula, Arnold, Philipp, Gögele, Clemens, Hahn, Judith, Breier, Annette, Meyer, Michael, Kohl, Benjamin, Schröpfer, Michaela, Schwarz, Silke
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014138/
https://ncbi.nlm.nih.gov/pubmed/31963350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020593
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