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SV40 Transfected Human Anterior Cruciate Ligament Derived Ligamentocytes—Suitable as a Human in Vitro Model for Ligament Reconstruction?

Cultured human primary cells have a limited lifespan undergoing dedifferentiation or senescence. Anterior cruciate ligaments (ACL) are hypocellular but tissue engineering (TE) requires high cell numbers. Simian virus (SV) 40 tumor (T) antigen expression could extend the lifespan of cells. This study...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Schulze-Tanzil, Gundula, Arnold, Philipp, Gögele, Clemens, Hahn, Judith, Breier, Annette, Meyer, Michael, Kohl, Benjamin, Schröpfer, Michaela, Schwarz, Silke
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014138/
https://ncbi.nlm.nih.gov/pubmed/31963350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020593
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