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GRK2-Mediated Crosstalk Between β-Adrenergic and Angiotensin II Receptors Enhances Adrenocortical Aldosterone Production In Vitro and In Vivo

Aldosterone is produced by adrenocortical zona glomerulosa (AZG) cells in response to angiotensin II (AngII) acting through its type I receptors (AT(1)Rs). AT(1)R is a G protein-coupled receptor (GPCR) that induces aldosterone via both G proteins and the adapter protein βarrestin1, which binds the r...

詳細記述

保存先:
書誌詳細
出版年:Int J Mol Sci
主要な著者: Pollard, Celina M., Ghandour, Jennifer, Cora, Natalie, Perez, Arianna, Parker, Barbara M., Desimine, Victoria L., Wertz, Shelby L., Pereyra, Janelle M., Ferraino, Krysten E., Patel, Jainika J., Lymperopoulos, Anastasios
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013621/
https://ncbi.nlm.nih.gov/pubmed/31963151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020574
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