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GRK2-Mediated Crosstalk Between β-Adrenergic and Angiotensin II Receptors Enhances Adrenocortical Aldosterone Production In Vitro and In Vivo

Aldosterone is produced by adrenocortical zona glomerulosa (AZG) cells in response to angiotensin II (AngII) acting through its type I receptors (AT(1)Rs). AT(1)R is a G protein-coupled receptor (GPCR) that induces aldosterone via both G proteins and the adapter protein βarrestin1, which binds the r...

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書目詳細資料
發表在:Int J Mol Sci
Main Authors: Pollard, Celina M., Ghandour, Jennifer, Cora, Natalie, Perez, Arianna, Parker, Barbara M., Desimine, Victoria L., Wertz, Shelby L., Pereyra, Janelle M., Ferraino, Krysten E., Patel, Jainika J., Lymperopoulos, Anastasios
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013621/
https://ncbi.nlm.nih.gov/pubmed/31963151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020574
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