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GRK2-Mediated Crosstalk Between β-Adrenergic and Angiotensin II Receptors Enhances Adrenocortical Aldosterone Production In Vitro and In Vivo

Aldosterone is produced by adrenocortical zona glomerulosa (AZG) cells in response to angiotensin II (AngII) acting through its type I receptors (AT(1)Rs). AT(1)R is a G protein-coupled receptor (GPCR) that induces aldosterone via both G proteins and the adapter protein βarrestin1, which binds the r...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Int J Mol Sci
मुख्य लेखकों: Pollard, Celina M., Ghandour, Jennifer, Cora, Natalie, Perez, Arianna, Parker, Barbara M., Desimine, Victoria L., Wertz, Shelby L., Pereyra, Janelle M., Ferraino, Krysten E., Patel, Jainika J., Lymperopoulos, Anastasios
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013621/
https://ncbi.nlm.nih.gov/pubmed/31963151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020574
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