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Engineering of Effector Domains for Targeted DNA Methylation with Reduced Off-Target Effects
Epigenome editing is a promising technology, potentially allowing the stable reprogramming of gene expression profiles without alteration of the DNA sequence. Targeted DNA methylation has been successfully documented by many groups for silencing selected genes, but recent publications have raised co...
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| 出版年: | Int J Mol Sci |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7013458/ https://ncbi.nlm.nih.gov/pubmed/31941101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020502 |
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