Llwytho...

Engineering of Effector Domains for Targeted DNA Methylation with Reduced Off-Target Effects

Epigenome editing is a promising technology, potentially allowing the stable reprogramming of gene expression profiles without alteration of the DNA sequence. Targeted DNA methylation has been successfully documented by many groups for silencing selected genes, but recent publications have raised co...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Hofacker, Daniel, Broche, Julian, Laistner, Laura, Adam, Sabrina, Bashtrykov, Pavel, Jeltsch, Albert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013458/
https://ncbi.nlm.nih.gov/pubmed/31941101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020502
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!