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Gilteritinib is a clinically active FLT3 inhibitor with broad activity against FLT3 kinase domain mutations
Gilteritinib is the first FMS-like tyrosine kinase 3 (FLT3) tyrosine kinase inhibitor (TKI) approved as monotherapy in acute myeloid leukemia with FLT3 internal tandem duplication and D835/I836 tyrosine kinase domain (TKD) mutations. Sequencing studies in patients have uncovered less common, noncano...
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| Publicado no: | Blood Adv |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7013266/ https://ncbi.nlm.nih.gov/pubmed/32040554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000919 |
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