Senescence-Associated Metabolomic Phenotype in Primary and iPSC-Derived Mesenchymal Stromal Cells

Long-term culture of primary cells is characterized by functional and secretory changes, which ultimately result in replicative senescence. It is largely unclear how the metabolome of cells changes during replicative senescence and if such changes are consistent across different cell types. We have...

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Udgivet i:Stem Cell Reports
Main Authors: Fernandez-Rebollo, Eduardo, Franzen, Julia, Goetzke, Roman, Hollmann, Jonathan, Ostrowska, Alina, Oliverio, Matteo, Sieben, Torsten, Rath, Björn, Kornfeld, Jan-Wilhelm, Wagner, Wolfgang
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013233/
https://ncbi.nlm.nih.gov/pubmed/31983656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.12.012
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