Senescence-Associated Metabolomic Phenotype in Primary and iPSC-Derived Mesenchymal Stromal Cells

Long-term culture of primary cells is characterized by functional and secretory changes, which ultimately result in replicative senescence. It is largely unclear how the metabolome of cells changes during replicative senescence and if such changes are consistent across different cell types. We have...

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Publicado en:Stem Cell Reports
Main Authors: Fernandez-Rebollo, Eduardo, Franzen, Julia, Goetzke, Roman, Hollmann, Jonathan, Ostrowska, Alina, Oliverio, Matteo, Sieben, Torsten, Rath, Björn, Kornfeld, Jan-Wilhelm, Wagner, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013233/
https://ncbi.nlm.nih.gov/pubmed/31983656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.12.012
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