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Fisetin regulates gut microbiota to decrease CCR9(+)/CXCR3(+)/CD4(+) T-lymphocyte count and IL-12 secretion to alleviate premature ovarian failure in mice

Currently, there are no studies reporting the efficacy of fisetin in premature ovarian failure (POF). In this study, using mouse and Caenorhabditis elegans models, we found that fisetin not only significantly reversed ovarian damage in POF mice, but also effectively increased C. elegans lifespan and...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Lin, Jiajia, Nie, Xiaoli, Xiong, Ying, Gong, Zhangbin, Chen, Jiulin, Chen, Chuan, Huang, Yongyi, Liu, Te
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013230/
https://ncbi.nlm.nih.gov/pubmed/32051749
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