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Biguanides in combination with olaparib limits tumorigenesis of drug‐resistant ovarian cancer cells through inhibition of Snail

Ovarian cancer is the most lethal gynecological malignancy. Currently, new chemotherapeutic strategies are required to improve patient outcome and survival. Biguanides, classic anti‐diabetic drugs, have gained importance for theiri antitumor potency demonstrated by various studies. Olaparib is a PAR...

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Publicado en:Cancer Med
Main Authors: Wang, Qiong, López‐Ozuna, Vanessa M., Baloch, Tahira, Bithras, Joanne, Amin, Oreekha, Kessous, Roy, Kogan, Liron, Laskov, Ido, Yasmeen, Amber
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013055/
https://ncbi.nlm.nih.gov/pubmed/31863638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2738
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