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Stimulation of histamine H(4) receptors increases the production of IL‐9 in Th9 polarized cells

BACKGROUND AND PURPOSE: Th9 cells represent a recently defined subset of CD4(+) T‐helper cells, characterized by a high production of IL‐9. They are found at increased frequency in lesions of atopic dermatitis, where IL‐9 is also elevated. As histamine is up‐regulated in lesions of inflammatory skin...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Schaper‐Gerhardt, Katrin, Wohlert, Mareike, Mommert, Susanne, Kietzmann, Manfred, Werfel, Thomas, Gutzmer, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012944/
https://ncbi.nlm.nih.gov/pubmed/30589077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14566
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