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The Anaphylatoxin C3a Receptor Expression on Human M2 Macrophages Is Down-Regulated by Stimulating the Histamine H4 Receptor and the IL-4 Receptor

The anaphylatoxin C3a triggers inflammation by binding to its specific G-protein-coupled C3a receptor (C3aR). Since the number of C3aR, which is expressed on the cell surface, affects the response to C3a, we investigated the expression levels of C3aR on human M2 macrophages in allergic situations wh...

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Pubblicato in:J Innate Immun
Autori principali: Mommert, Susanne, Aslan, Derya, Ratz, Lisanne, Stark, Holger, Gutzmer, Ralf, Werfel, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757164/
https://ncbi.nlm.nih.gov/pubmed/30032131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000490426
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