Quantitative SUMO proteomics identifies PIAS1 substrates involved in cell migration and motility

The protein inhibitor of activated STAT1 (PIAS1) is an E3 SUMO ligase that plays important roles in various cellular pathways. Increasing evidence shows that PIAS1 is overexpressed in various human malignancies, including prostate and lung cancers. Here we used quantitative SUMO proteomics to identi...

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Udgivet i:Nat Commun
Main Authors: Li, Chongyang, McManus, Francis P., Plutoni, Cédric, Pascariu, Cristina Mirela, Nelson, Trent, Alberici Delsin, Lara Elis, Emery, Gregory, Thibault, Pierre
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012886/
https://ncbi.nlm.nih.gov/pubmed/32047143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14581-w
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