Androgen receptor-binding sites are highly mutated in prostate cancer

Androgen receptor (AR) signalling is essential in nearly all prostate cancers. Any alterations to AR-mediated transcription can have a profound effect on carcinogenesis and tumor growth. While mutations of the AR protein have been extensively studied, little is known about those somatic mutations th...

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Vydáno v:Nat Commun
Hlavní autoři: Morova, Tunç, McNeill, Daniel R., Lallous, Nada, Gönen, Mehmet, Dalal, Kush, Wilson, David M., Gürsoy, Attila, Keskin, Özlem, Lack, Nathan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012874/
https://ncbi.nlm.nih.gov/pubmed/32047165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14644-y
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