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Designing minimal genomes using whole-cell models

In the future, entire genomes tailored to specific functions and environments could be designed using computational tools. However, computational tools for genome design are currently scarce. Here we present algorithms that enable the use of design-simulate-test cycles for genome design, using genom...

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Publicat a:Nat Commun
Autors principals: Rees-Garbutt, Joshua, Chalkley, Oliver, Landon, Sophie, Purcell, Oliver, Marucci, Lucia, Grierson, Claire
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012841/
https://ncbi.nlm.nih.gov/pubmed/32047145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14545-0
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