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Designing minimal genomes using whole-cell models

In the future, entire genomes tailored to specific functions and environments could be designed using computational tools. However, computational tools for genome design are currently scarce. Here we present algorithms that enable the use of design-simulate-test cycles for genome design, using genom...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rees-Garbutt, Joshua, Chalkley, Oliver, Landon, Sophie, Purcell, Oliver, Marucci, Lucia, Grierson, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012841/
https://ncbi.nlm.nih.gov/pubmed/32047145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14545-0
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