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Cellular Uptake of Protic Ruthenium Complexes is Influenced by pH Dependent Passive Diffusion and Energy Dependent Efflux
The lipophilic vs. hydrophilic properties of three protic ruthenium compounds were studied as a function of pH. Specifically, we measured log(D(o/w)) values for [(N,N)(2)Ru(6,6’-dhbp)](2+) complexes (where N,N = 2,2’-bipyridine (1(A)), 1,10-phenanthroline (2(A)), 2,3-dihydro-[1,4]dioxino[2,3-f][1,10...
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| Publicat a: | J Inorg Biochem |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7012720/ https://ncbi.nlm.nih.gov/pubmed/31775072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2019.110922 |
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