Evidence of corticofugal tau spreading in patients with frontotemporal dementia

Common neurodegenerative diseases feature progressive accumulation of disease-specific protein aggregates in selectively vulnerable brain regions. Increasing experimental evidence suggests that misfolded disease proteins exhibit prion-like properties, including the ability to seed corruptive templat...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Kim, Eun-Joo, Hwang, Ji-Hye L., Gaus, Stephanie E., Nana, Alissa L., Deng, Jersey, Brown, Jesse A., Spina, Salvatore, Lee, Myung Jun, Ramos, Eliana Marisa, Grinberg, Lea T., Kramer, Joel H., Boxer, Adam L., Gorno-Tempini, Maria Luisa, Rosen, Howard J., Miller, Bruce L., Seeley, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012377/
https://ncbi.nlm.nih.gov/pubmed/31542807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02075-z
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