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Interferon regulatory factors 3 and 7 have distinct roles in the pathogenesis of alphavirus encephalomyelitis

Interferon (IFN) regulatory factors (IRFs) are important determinants of the innate response to infection. We evaluated the role(s) of combined and individual IRF deficiencies in the outcome of infection of C57BL/6 mice with Sindbis virus, an alphavirus that infects neurons and causes encephalomyeli...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Schultz, Kimberly L. W., Troisi, Elizabeth M., Baxter, Victoria K., Glowinski, Rebecca, Griffin, Diane E.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011693/
https://ncbi.nlm.nih.gov/pubmed/30451651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001174
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