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Interferon regulatory factors 3 and 7 have distinct roles in the pathogenesis of alphavirus encephalomyelitis

Interferon (IFN) regulatory factors (IRFs) are important determinants of the innate response to infection. We evaluated the role(s) of combined and individual IRF deficiencies in the outcome of infection of C57BL/6 mice with Sindbis virus, an alphavirus that infects neurons and causes encephalomyeli...

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Publicado en:J Gen Virol
Autores principales: Schultz, Kimberly L. W., Troisi, Elizabeth M., Baxter, Victoria K., Glowinski, Rebecca, Griffin, Diane E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Microbiology Society 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011693/
https://ncbi.nlm.nih.gov/pubmed/30451651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001174
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