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Dissecting pharmacological effects of chloroquine in cancer treatment: interference with inflammatory signaling pathways
Chloroquines are 4‐aminoquinoline‐based drugs mainly used to treat malaria. At pharmacological concentrations, they have significant effects on tissue homeostasis, targeting diverse signaling pathways in mammalian cells. A key target pathway is autophagy, which regulates macromolecule turnover in th...
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| Izdano u: | Immunology |
|---|---|
| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7011648/ https://ncbi.nlm.nih.gov/pubmed/31782148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13160 |
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