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Dissecting pharmacological effects of chloroquine in cancer treatment: interference with inflammatory signaling pathways

Chloroquines are 4‐aminoquinoline‐based drugs mainly used to treat malaria. At pharmacological concentrations, they have significant effects on tissue homeostasis, targeting diverse signaling pathways in mammalian cells. A key target pathway is autophagy, which regulates macromolecule turnover in th...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Varisli, Lokman, Cen, Osman, Vlahopoulos, Spiros
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011648/
https://ncbi.nlm.nih.gov/pubmed/31782148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13160
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