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Synthesis of Densely Functionalized Pyrimidouracils by Nickel(II)-Catalyzed Isocyanide Insertion
[Image: see text] A robust nickel-catalyzed oxidative isocyanide insertion/C–H amination by reaction of readily available N-uracil-amidines with isocyanides affording polysubstituted pyrimidouracils has been reported. The reaction proceeds in moderate to quantitative yield, under mild conditions (i....
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| Vydáno v: | Org Lett |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American
Chemical Society
2020
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7011176/ https://ncbi.nlm.nih.gov/pubmed/31942797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b04387 |
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