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Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy‐induced bone loss
Osteoclasts are multinucleated cells derived from the monocyte/macrophage cell lineage under the regulation of receptor activator of nuclear factor‐κB ligand (RANKL). In previous studies, stimulation by RANKL during osteoclastogenesis was shown to induce a metabolic switch to enhanced glycolytic met...
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| Опубликовано в: : | J Cell Mol Med |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7011148/ https://ncbi.nlm.nih.gov/pubmed/31880389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14912 |
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