Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy‐induced bone loss

Osteoclasts are multinucleated cells derived from the monocyte/macrophage cell lineage under the regulation of receptor activator of nuclear factor‐κB ligand (RANKL). In previous studies, stimulation by RANKL during osteoclastogenesis was shown to induce a metabolic switch to enhanced glycolytic met...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Wang, Jia, Guan, Hanfeng, Liu, Hui, Lei, Zuowei, Kang, Honglei, Guo, Qian, Dong, Yimin, Liu, Huiyong, Sun, Yunlong, Fang, Zhong, Li, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011148/
https://ncbi.nlm.nih.gov/pubmed/31880389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14912
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