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Down Syndrome Reduces the Sedative Effect of Midazolam in Pediatric Cardiovascular Surgical Patients

Down syndrome (DS) is frequently comorbid with congenital heart disease and has recently been shown to reduce the sedative effect of benzodiazepine (BDZ)-class anesthesia but this effect in a clinical setting has not been studied. Therefore, this study compared midazolam sedation after heart surgery...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Matsuishi, Yujiro, Sakuramoto, Hideaki, Hoshino, Haruhiko, Shimojo, Nobutake, Enomoto, Yuki, Mathis, Bryan J., Hiramatsu, Yuji, Inoue, Yoshiaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010829/
https://ncbi.nlm.nih.gov/pubmed/32041972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58283-1
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