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Down Syndrome Reduces the Sedative Effect of Midazolam in Pediatric Cardiovascular Surgical Patients

Down syndrome (DS) is frequently comorbid with congenital heart disease and has recently been shown to reduce the sedative effect of benzodiazepine (BDZ)-class anesthesia but this effect in a clinical setting has not been studied. Therefore, this study compared midazolam sedation after heart surgery...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Matsuishi, Yujiro, Sakuramoto, Hideaki, Hoshino, Haruhiko, Shimojo, Nobutake, Enomoto, Yuki, Mathis, Bryan J., Hiramatsu, Yuji, Inoue, Yoshiaki
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010829/
https://ncbi.nlm.nih.gov/pubmed/32041972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58283-1
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