Nandrolone induces a stem cell-like phenotype in human hepatocarcinoma-derived cell line inhibiting mitochondrial respiratory activity

Nandrolone is a testosterone analogue with anabolic properties commonly abused worldwide, recently utilized also as therapeutic agent in chronic diseases, cancer included. Here we investigated the impact of nandrolone on the metabolic phenotype in HepG2 cell line. The results attained show that phar...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Agriesti, Francesca, Tataranni, Tiziana, Pacelli, Consiglia, Scrima, Rosella, Laurenzana, Ilaria, Ruggieri, Vitalba, Cela, Olga, Mazzoccoli, Carmela, Salerno, Monica, Sessa, Francesco, Sani, Gabriele, Pomara, Cristoforo, Capitanio, Nazzareno, Piccoli, Claudia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010785/
https://ncbi.nlm.nih.gov/pubmed/32041983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58871-1
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