IgSF11 regulates osteoclast differentiation through association with the scaffold protein PSD-95

Osteoclasts are multinucleated, giant cells derived from myeloid progenitors. While receptor activator of NF-κB ligand (RANKL) stimulation is the primary driver of osteoclast differentiation, additional signaling further contributes to osteoclast maturation. Here, we demonstrate that immunoglobulin...

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Vydáno v:Bone Res
Hlavní autoři: Kim, Hyunsoo, Takegahara, Noriko, Walsh, Matthew C., Middleton, Sarah A., Yu, Jiyeon, Shirakawa, Jumpei, Ueda, Jun, Fujihara, Yoshitaka, Ikawa, Masahito, Ishii, Masaru, Kim, Junhyong, Choi, Yongwon
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010662/
https://ncbi.nlm.nih.gov/pubmed/32047704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-019-0080-9
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