Developmental Population Pharmacokinetics and Dosing Optimization of Cefepime in Neonates and Young Infants

OBJECTIVE: Cefepime is used to treat severe infections in neonates. Pharmacokinetic data have only been evaluated among preterm neonates and population pharmacokinetic model lacked external validation. Hence, our aim is to obtain the population pharmacokinetic parameters of cefepime with large sampl...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Principais autores: Zhao, Yang, Yao, Bu-Fan, Kou, Chen, Xu, Hai-Yan, Tang, Bo-Hao, Wu, Yue-E, Hao, Guo-Xiang, Zhang, Xin-Ping, Zhao, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010644/
https://ncbi.nlm.nih.gov/pubmed/32116695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00014
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