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A Double Humanized BLT-mice Model Featuring a Stable Human-Like Gut Microbiome and Human Immune System

Humanized mice (hu-mice) that feature a functional human immune system have fundamentally changed the study of human pathogens and disease. They can be used to model diseases that are otherwise difficult or impossible to study in humans or other animal models. The gut microbiome can have a profound...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Daharsh, Lance, Zhang, Jianshui, Ramer-Tait, Amanda, Li, Qingsheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7009290/
https://ncbi.nlm.nih.gov/pubmed/31524867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/59773
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