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A Double Humanized BLT-mice Model Featuring a Stable Human-Like Gut Microbiome and Human Immune System

Humanized mice (hu-mice) that feature a functional human immune system have fundamentally changed the study of human pathogens and disease. They can be used to model diseases that are otherwise difficult or impossible to study in humans or other animal models. The gut microbiome can have a profound...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Daharsh, Lance, Zhang, Jianshui, Ramer-Tait, Amanda, Li, Qingsheng
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7009290/
https://ncbi.nlm.nih.gov/pubmed/31524867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/59773
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