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Measuring local conformations and conformational disorder of (Cy3)(2) dimer labeled DNA fork junctions using absorbance, circular dichroism and two-dimensional fluorescence spectroscopy

The sugar-phosphate backbone of DNA near single-stranded (ss)—double-stranded (ds) junctions likely fluctuates within a broad distribution of conformations to permit the proper binding of genome regulatory proteins that function at these sites. In this work, we use absorbance, circular dichroism (CD...

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Bibliografiske detaljer
Udgivet i:Faraday Discuss
Main Authors: Heussman, Dylan, Kittell, Justin, Kringle, Loni, Tamimi, Amr, von Hippel, Peter H., Marcus, Andrew H.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008976/
https://ncbi.nlm.nih.gov/pubmed/31038134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8fd00245b
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