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Structure of an active human histone pre-mRNA 3′-end processing machinery()

The 3′-end processing machinery for metazoan replication-dependent histone pre-mRNAs contains the U7 snRNP and shares the key cleavage module with the canonical cleavage/polyadenylation machinery. We reconstituted an active human histone pre-mRNA processing machinery using 13 recombinant proteins an...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Sun, Yadong, Zhang, Yixiao, Aik, Wei Shen, Yang, Xiao-Cui, Marzluff, William F., Walz, Thomas, Dominski, Zbigniew, Tong, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008720/
https://ncbi.nlm.nih.gov/pubmed/32029631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz7758
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