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Deletion of the RNA regulator HuR in tumor associated microglia and macrophages stimulates antitumor immunity and attenuates glioma growth

Glioblastoma is a malignant brain tumor that portends a poor prognosis. Its resilience, in part, is related to a remarkable capacity for manipulating the microenvironment to promote its growth and survival. Microglia/macrophages are prime targets, being drawn into the tumor and stimulated to produce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Glia
Hauptverfasser: Wang, Jiping, Leavenworth, Jianmei, Hjelmeland, Anita B., Smith, Reed, Patel, Neha, Borg, Ben, Si, Ying, King, Peter H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008520/
https://ncbi.nlm.nih.gov/pubmed/31400163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23696
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