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Characterization of the apicoplast-localized enzyme TgUroD in Toxoplasma gondii reveals a key role of the apicoplast in heme biosynthesis

Apicomplexan parasites such as Toxoplasma gondii possess an unusual heme biosynthesis pathway whose enzymes localize to the mitochondrion, cytosol, or apicoplast, a nonphotosynthetic plastid present in most apicomplexans. To characterize the involvement of the apicoplast in the T. gondii heme biosyn...

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Publicado en:J Biol Chem
Autores principales: Tjhin, Edwin T., Hayward, Jenni A., McFadden, Geoffrey I., van Dooren, Giel G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008375/
https://ncbi.nlm.nih.gov/pubmed/31914409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011605
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