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Characterization of the Chloroquine Resistance Transporter Homologue in Toxoplasma gondii

Mutations in the Plasmodium falciparum chloroquine resistance transporter (PfCRT) protein confer resistance to the antimalarial drug chloroquine. PfCRT localizes to the parasite digestive vacuole, the site of chloroquine action, where it mediates resistance by transporting chloroquine out of the dig...

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Bibliografske podrobnosti
izdano v:Eukaryot Cell
Main Authors: Warring, Sally D., Dou, Zhicheng, Carruthers, Vern B., McFadden, Geoffrey I., van Dooren, Giel G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248696/
https://ncbi.nlm.nih.gov/pubmed/24859994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00027-14
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