Long-term Effects of the Janus Kinase 1/2 Inhibitor Ruxolitinib on Pulmonary Hypertension and the Cardiac Function in a Patient with Myelofibrosis

Constitutive activation of the Janus kinase/signal transduction and activator of transcription (JAK-STAT) signaling pathway plays a central role in the pathogenesis of myelofibrosis (MF) and pulmonary hypertension (PH) is a known complication of MF. On the other hand, it has been proposed that the J...

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Detalhes bibliográficos
Publicado no:Intern Med
Main Authors: Miyawaki, Hiroshi, Kioka, Hidetaka, Sato, Kazuaki, Kurashige, Masako, Ozawa, Takayuki, Shibayama, Hirohiko, Hikoso, Shungo, Morii, Eiichi, Yamauchi-Takihara, Keiko, Sakata, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Internal Medicine 2019
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008043/
https://ncbi.nlm.nih.gov/pubmed/31534088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.3528-19
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