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Efficacy of Ruxolitinib for Myelofibrosis

INTRODUCTION: The discovery of the activating JAK2V617F mutation in patients with myelofibrosis (MF) led to the development of JAK2 inhibitors. The first such inhibitor to enter clinical trials was ruxolitinib. This review summarizes pre-clinical and clinical data of ruxolitinib in MF. AREAS COVERED...

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Detalhes bibliográficos
Publicado no:Expert Opin Pharmacother
Main Authors: Santos, Fabio P S, Verstovsek, Srdan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824286/
https://ncbi.nlm.nih.gov/pubmed/24856675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14656566.2014.923404
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