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Efficacy of Ruxolitinib for Myelofibrosis

INTRODUCTION: The discovery of the activating JAK2V617F mutation in patients with myelofibrosis (MF) led to the development of JAK2 inhibitors. The first such inhibitor to enter clinical trials was ruxolitinib. This review summarizes pre-clinical and clinical data of ruxolitinib in MF. AREAS COVERED...

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Dettagli Bibliografici
Pubblicato in:Expert Opin Pharmacother
Autori principali: Santos, Fabio P S, Verstovsek, Srdan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824286/
https://ncbi.nlm.nih.gov/pubmed/24856675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14656566.2014.923404
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