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Efficacy of Ruxolitinib for Myelofibrosis

INTRODUCTION: The discovery of the activating JAK2V617F mutation in patients with myelofibrosis (MF) led to the development of JAK2 inhibitors. The first such inhibitor to enter clinical trials was ruxolitinib. This review summarizes pre-clinical and clinical data of ruxolitinib in MF. AREAS COVERED...

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Dades bibliogràfiques
Publicat a:Expert Opin Pharmacother
Autors principals: Santos, Fabio P S, Verstovsek, Srdan
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824286/
https://ncbi.nlm.nih.gov/pubmed/24856675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14656566.2014.923404
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