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Annulation of Hydrazones and Alkynes via Rhodium(III)-Catalyzed Dual C–H Activation: Synthesis of Pyrrolopyridazines and Azolopyridazines

Hydrazones readily synthesized from N-aminopyrroles or N-aminoazoles and aldehydes undergo Rh(III)-catalyzed dual C−H activation and coupling with aryl and alkyl substituted alkynes to give pyrrolopyridazines or azolopyridazines, respectively. This transformation represents a rare example of hydrazo...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Streit, Andrew D., Zoll, Adam J., Hoang, Gia L., Ellman, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007857/
https://ncbi.nlm.nih.gov/pubmed/31977232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c00186
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