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C1-CBP-Vancomycin: Impact of a Vancomycin C-terminus Trimethylammonium Cation on Pharmacological Properties and Insights into its Newly Introduced Mechanism of Action
C1-CBP-vancomycin (3) was examined alongside CBP-vancomycin for susceptibility to acquired resistance upon serial exposure against two vancomycin-resistant enterococci strains where its activity proved more durable and remarkably better than many current therapies. Combined with earlier studies, thi...
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| Publicado no: | J Org Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7007832/ https://ncbi.nlm.nih.gov/pubmed/31670958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02314 |
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