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Long-term caloric restriction activates the myocardial SIRT1/AMPK/PGC-1α pathway in C57BL/6J male mice

BACKGROUND: Caloric restriction (CR) can help in improving heart function. There is as yet no consensus on the mechanism of the effect of CR. Silent mating-type information regulation 1 (SIRT1), adenosine monophosphate-activated protein kinase (AMPK), and mTOR are key players in metabolic stress man...

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Bibliographische Detailangaben
Veröffentlicht in:Food Nutr Res
Hauptverfasser: Ma, Lina, Wang, Rong, Wang, Hongjuan, Zhang, Yaxin, Zhao, Zhiwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Open Academia 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007760/
https://ncbi.nlm.nih.gov/pubmed/32082101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29219/fnr.v64.3668
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