Vitamin D supplementation improves SIRT1, Irisin, and glucose indices in overweight or obese type 2 diabetic patients: a double-blind randomized placebo-controlled clinical trial

BACKGROUND: Vitamin D (VD) may increase sirtuin 1 (SIRT1) and subsequently PPAR-γ coactivator 1α (PGC-1α) and irisin levels and these improvements may reduce insulin resistance (IR). The aim was to assess the effects of vitamin D supplementation on SIRT1, irisin, and IR in overweight/obese type 2 di...

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Pubblicato in:BMC Fam Pract
Autori principali: Safarpour, Peivasteh, Daneshi-Maskooni, Milad, Vafa, Mohammadreza, Nourbakhsh, Mitra, Janani, Leila, Maddah, Mohsen, Amiri, Fatemeh-Sadat, Mohammadi, Fereshteh, Sadeghi, Homa
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007689/
https://ncbi.nlm.nih.gov/pubmed/32033527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12875-020-1096-3
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