Scd1 controls de novo beige fat biogenesis through succinate-dependent regulation of mitochondrial complex II

Preadipocytes can give rise to either white adipocytes or beige adipocytes. Owing to their distinct abilities in nutrient storage and energy expenditure, strategies that specifically promote “beiging” of adipocytes hold great promise for counterbalancing obesity and metabolic diseases. Yet, factors...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Liu, Keli, Lin, Liangyu, Li, Qing, Xue, Yueqing, Zheng, Fanjun, Wang, Guan, Zheng, Chunxing, Du, Liming, Hu, Mingyuan, Huang, Yin, Shao, Changshun, Kong, Xiangyin, Melino, Gerry, Shi, Yufang, Wang, Ying
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007576/
https://ncbi.nlm.nih.gov/pubmed/31953260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914553117
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