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Scd1 controls de novo beige fat biogenesis through succinate-dependent regulation of mitochondrial complex II

Preadipocytes can give rise to either white adipocytes or beige adipocytes. Owing to their distinct abilities in nutrient storage and energy expenditure, strategies that specifically promote “beiging” of adipocytes hold great promise for counterbalancing obesity and metabolic diseases. Yet, factors...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Liu, Keli, Lin, Liangyu, Li, Qing, Xue, Yueqing, Zheng, Fanjun, Wang, Guan, Zheng, Chunxing, Du, Liming, Hu, Mingyuan, Huang, Yin, Shao, Changshun, Kong, Xiangyin, Melino, Gerry, Shi, Yufang, Wang, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007576/
https://ncbi.nlm.nih.gov/pubmed/31953260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914553117
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