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A 300-fold enhancement of imino nucleic acid resonances by hyperpolarized water provides a new window for probing RNA refolding by 1D and 2D NMR

NMR sensitivity-enhancement methods involving hyperpolarized water could be of importance for solution-state biophysical investigations. Hyperpolarized water (HyperW) can enhance the (1)H NMR signals of exchangeable sites by orders of magnitude over their thermal counterparts, while providing insigh...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Novakovic, Mihajlo, Olsen, Gregory L., Pintér, György, Hymon, Daniel, Fürtig, Boris, Schwalbe, Harald, Frydman, Lucio
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007528/
https://ncbi.nlm.nih.gov/pubmed/31949004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916956117
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