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The clinical potential of gene editing as a tool to engineer cell-based therapeutics
The clinical application of ex vivo gene edited cell therapies first began a decade ago with zinc finger nuclease editing of autologous CD4(+) T-cells. Editing aimed to disrupt expression of the human immunodeficiency virus co-receptor gene CCR5, with the goal of yielding cells resistant to viral en...
Gorde:
| Argitaratua izan da: | Clin Transl Med |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Springer Berlin Heidelberg
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7007464/ https://ncbi.nlm.nih.gov/pubmed/32034584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-020-0268-z |
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