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Dynamic in vitro intestinal barrier model coupled to chip-based liquid chromatography mass spectrometry for oral bioavailability studies

In oral bioavailability studies, evaluation of the absorption and transport of drugs and food components across the intestinal barrier is crucial. Advances in the field of organ-on-a-chip technology have resulted in a dynamic gut-on-a-chip model that better mimics the in vivo microenvironment of the...

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Detalles Bibliográficos
Publicado en:Anal Bioanal Chem
Main Authors: Santbergen, Milou J. C., van der Zande, Meike, Gerssen, Arjen, Bouwmeester, Hans, Nielen, Michel W. F.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007416/
https://ncbi.nlm.nih.gov/pubmed/31865418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-019-02336-6
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