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Dynamic in vitro intestinal barrier model coupled to chip-based liquid chromatography mass spectrometry for oral bioavailability studies

In oral bioavailability studies, evaluation of the absorption and transport of drugs and food components across the intestinal barrier is crucial. Advances in the field of organ-on-a-chip technology have resulted in a dynamic gut-on-a-chip model that better mimics the in vivo microenvironment of the...

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Publicat a:Anal Bioanal Chem
Autors principals: Santbergen, Milou J. C., van der Zande, Meike, Gerssen, Arjen, Bouwmeester, Hans, Nielen, Michel W. F.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007416/
https://ncbi.nlm.nih.gov/pubmed/31865418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-019-02336-6
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